Bond Elut Focus features a unique amide-functionalized, polar-enhanced sorbent technology delivering outstanding retention. The extraction method eliminates the complex pH adjustments necessary with ion exchange and mixed mode methods. The unique ligand chemistry on the sorbent dramatically increases the retention of basic analytes.;The improved retention for polar analytes with Focus allows the use of a strong “power rinse” without causing analyte loss. Rigorous washes using 10 to 20% MeOH can be used to aggressively remove endogenous matrix interferences. For very polar analytes that are held by strictly polar interactions, washes of up to 100% can be used.
